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V1RL1 - THE Human Pheromone Receptor
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eldros
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V1RL1 - THE Human Pheromone Receptor
08-03-2015 10:09 AM

Didn't see this posted here yet.

This come from a 2000 research paper from Nature in which a group from Rockefeller U. and Yale SOM discover an active gene in humans that shares homology with the v1r and v2r pheromone receptor families of rodents.

http://www.nature.com/ng/journal/v26/n1/...00_18.html
Quote: A putative pheromone receptor gene expressed in human olfactory mucosa

Pheromones elicit specific behavioural responses and physiological alterations in recipients of the same species. In mammals, these chemical signals are recognized within the nasal cavity by sensory neurons that express pheromone receptors. In rodents, these receptors are thought to be represented by two large multigene families, comprising the V1r and V2r genes, which encode seven-transmembrane proteins. Although pheromonal effects have been demonstrated in humans, V1R or V2R counterparts of the rodent genes have yet to be characterized.

Quote:The researchers screened a wide range of human tissues to determine where V1RL1 gene expression takes place. They found expression consistently in the olfactory mucosa, which is used to detect smells, but not in most other tissues. Expression was detected in brain, lung and kidney, but not reproducibly, suggesting low expression levels in these organs, which may not be functionally significant.
(This post was last modified: 08-03-2015 10:21 AM by eldros.)
08-03-2015 10:09 AM
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Caroline91
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Post: #2
RE: V1RL1 - THE Human Pheromone Receptor
08-05-2015 12:53 AM

Thanks for your sharing! After read the post, I know better about how this gene expression take place.
08-05-2015 12:53 AM
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