if you apply a moderate dose of Androstadienone and feel mild-moderate depression and lethargy,not to worry! there's a way to counter this.you shouldn't wear this phero solo,this molecule work better with other mones in the mix and can also fight that unwanted downer.Androstadienone should go together with sexual/alpha mixes.first apply your sexual/alpha mones to neck and apply a dab under nose.wait for at least 2 minutes,THEN apply the Androstadienone .using this method you can counter that shitty feeling.work for me everytime.remember sexual/alpha first all to neck area,not the other way around.this method only work if you apply moderate amount of that depressing juice,with high dose im afraid no mones can help you.moderation is the key