Is my understanding that the Methoxyestratetraenone from Sigma-Aldrich, is in a non-liquid state, correct? How would you inevitably use it as a fluid concentrate, what would that require?

(02-02-2010 9:18 AM)Domnk Wrote:  

Is my understanding that the Methoxyestratetraenone from Sigma-Aldrich, is in a non-liquid state, correct? How would you inevitably use it as a fluid concentrate, what would that require?

Sorry, Zeph, last post was blanked, what was that? (I had to switch from firefox to IE to use the main text box and have it function)

Sigma Aldrich doesn't carry Methoxyestratetraenone - 1, 3, 5(10), 7-Estratetraen-3-ol-17-one methyl ether any longer.

They carry Equillin - 1,3,5(10),7-Estratetraen-3-ol-17-one.

The methyl ether makes a difference in how this works. The only current US supplier that I know of is Steraloids, and they don't plan on making more than the little they now have in stock.

Diane

Ah crap. I thought it had posted. Crazy ghosts in the system is doing weird things. o_O;;

Anyhow, I said something like I'd give my input until someone like perhaps gegogi, diane or tisha who may have more experience chimes in.

If its in solid state, you can try dissolving it in perfumer's alcohol. I don't think you need any special tools unless you wanted an exact number as to the concentration of what you're using. You can probably also use the same unscented alcohol solution that AD and other companies use.

Best person to ask is probably Diane seeing as how she's actually making it from scratch.

Perfumer's alcohol is isopropyl alcohol, isopropyl myristate, and a denaturing agent. Isopropyl alcohol is not ideal for dissolving steroid pheromones. A better choice is ethanol, but you'll need to check with your state to see if it is legal to purchase a high grade ethanol where you live. Don't try to dissolve these in low grade ethanol (150 proof) as these contain a good deal of water that will inhibit the dissolving of these substances.

Methoxy-Estratetraenone is notoriously difficult to dissolve even in 190 to 200 proof ethanol. It will, however dissolve if the ethanol is gently warmed. Be careful to only warm the ethanol in a water bath, however, and never place your container directly on a burner or on a hot plate, because the flash point of ethanol is very low, and alcohol burns are not fun.

Also, be aware that the volume of ethanol will increase dramatically with heating, so it is important that you measure your total volume of ethanol before you warm it, and that you leave sufficient empty space in your container to contain the extra volume. The volume will return to its normal state as the solution cools. Also, be sure that your container of alcohol is capped and that you do not warm the mixture too much, because the alcohol will evaporate if you leave the container open, and the cap will explode if you heat the mixture too much. Alcohol has a very low boiling point.

Diane

Speaking from experience (I worked in a chemical plant for almost 10 years) you will want to be very careful, I've seen alcohol fires on larger scale and Diane is right, it isn't fun.

Yup... so remember... water bath... warm, not hot... and don't leave it untended. I don't even use a hot plate for this. I use heated water in a beaker on the lab bench, which I immerse the container of alcohol in... no chance for fire or explosion that way.

Diane

Hi,

In my enthousiasm I was looking up information about Methoxyestratetraenone so I typed in the formula in google (C18H20O2) and I stumbled upon this:

a synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy

On this page:

http://www.memidex.com/c18h20o2

That doesn't sound too positive, does it? Or did those people eat the Meo-ests?

I don't want to be negative, but also wanted to share this with you.

---

Koala's are known to only eat leaves from the eucalyptus tree.
They don't only get a full stomach of that, they also get stoned out of these leaves.
Can't nature be amazing?

Your not being negative at all. Those people did ingest it in pill form. I dont like meo est and I agree with Diane that its not something that should be sold as a pheromone. I know Androtics sells it though and new users over there who dont know any better are spraying high high dosages of it. While there is no proof it can cause problems pheromonally it still has caused cancer when inside the system. So I am wary of this one.


Thanks for sharing the articles

Tisha