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Doing some research trying to find something to help with my brain functions, there is a new type of drugs that is close to the NZT from the film limitless.

Like synth mones, nootropics is a relative new field. Does anyone have any experience using them?

This website seems to be the most active for nootropics info.

By reading some of the posts, like any supplement and like mones everyone has different effects. So it's not a magic pill that works for everyone. But just something else to give an edge in life. They give a warning also that this stuff is still EXPERIMENTAL, so use at your own risk.

List 1
List 2

Sample of info from list 1 :

Piracetam

(2-oxo-Pyrrolidine Acetamide) - is a derivative of the neurotransmitter GABA (Gamma Amino Butyric Acid). Chemically related to the amino acid Pyroglutamic Acid (Pyrrolidine Carboxylic acid), which occurs in cerebrospinal fluid and plays an important role in cognitive functioning.

Biochemical Effects

Enhances Brain Metabolism (By increasing Glucose Utilization, Blood & Oxygen Flow){Boosts mental energy & cerebral circulation}

Increases Cerebral Phospholipids & Cellular Membrane Fluidity (By interacting with the polar head moieties of the phospholipid bilayer) {Supports healthy neuron communication & structure}.

Supports Cognitive Receptors (By amplifying the density of the Muscarinic Cholinergic {Frontal Cortex, Striatum, & Hippocampus}, NMDA (N-Methyl-D-Aspartate) {Hippocampus}, & AMPA (Alpha-amino-3-hydroxy-5-Methyl-4-isoxazole-Propionic Acid) Cerebral Cortex Receptors {Strengthens neurotransmitter receptors involved in memory and neuroprotection}

Stimulates the Corpus Callosum, an area of the brain that controls communication between the left and right hemispheres (Increases communication between both hemispheres) {Involved in speech and creative thinking}.

Stimulates the Locus Coeruleus, (specialized neurons) {Involved in information processing, attention, cortical/behavioral arousal, learning and memory}

Inhibits Platelet Aggregation (By increasing Red-White blood cells & Platelet deformability, inhibiting thromboxane A2 synthetase or antagonism of thromboxane A2, reducing von Willebrand's factor & fibrinogen levels) {Supports Healthy Blood Flow}.

Decreases EEG complexity (Increases cooperatively of brain functional processing) {Positively effects Neuro-Electrical Functioning}.

Has a significant antioxidant effect.

Piracetam positively supports healthy cognitive & cardiovascular functioning by a multifaceted means of action.

Notes
Approved & used since 1970’s worldwide (Europe, Asia, and South American) for various health conditions. Recommended by many healthcare professionals and health organizations, such as the Life Extension Foundation, as a Nootropic.
Piracetum is the first step in the use of nootropics, it also stacks nicely with all of the following.

Dose
2-6 grams daily

When can I feel it?
Works within an hour to a few days.

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Aniracetam

Aniracetam (1-Anisoyl-2-pyrrolidinone) is a fat soluble potent analog of Piracetam.

Biochemical Effects
Similar to Piracetam, but due to its fat solubility its effects last longer and is far more potent.

Helps increase communication between your left and right sides of the brain, resulting in improved creatively, perception, and more.

Has an more potent AMPA receptor enhancing effect than Piracetam, resulting in better focus and concentration.

Been reported to be best ‘cetam for anti-anxiety effects

Dose
750-1500 mg Daily with meals

When can I feel it?
Works within an hour to a few days.

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Oxiracetam

(4-hydroxy-2-oxo-1-pyrrolidinacetamide) is a potent fast acting water soluble analog of Piracetam. Works faster than all other racetams.

Biochemical Effects
Similar to Piracetam, but much stronger than Aniracetam and far faster acting. The preferred premium Nootropic for the elite smart drug user.

Supports multiple aspects of Cognition

Boosts Brain ATP levels (Mental Energy)

Increase Choline Acetylcholinetranferase the neuro-enzyme that creates Acetylcholine (in the cerebral cortex, hippocampus and striatum) {Memory Support}

Dose
800-1600 mg Daily

When can I feel it?
Works within an hour to a few days.

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Pramiracetam

Pramiracetam (N-{2-(diisopropylamino)ethyl}-2-oxo-1-pyrrolidine-acetamide) is a fat soluble potent analog of Piracetam, the most potent Racetam compound being about 15 times stronger than Piracetam.

Dose
100-300mg daily

Availability
Sporadic due to customs issues.

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L-Huperzine

A is a natural plant alkaloid (extracted from Huperzia serrata), which quickly and potently boosts memory, learning, and concentration. Used worldwide for decades in adults and high school students. Is considered the most potent short term memory enhancer available.

Biochemical Effects

Potently raises Acetylcholine (main memory neurotransmitter) by inhibiting its breakdown from Acetylcholinesterase.

Strengthens the Brain's NMDA receptors (Enhances Focus, Learning, and Brain Functioning)

Dose
Take 200-400 mcg daily for best results with meals.

When can I feel it?
Works within an hour to a few days.

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Alpha GPC

(Alpha L-GlycerylPhosphorylCholine), also known as choline alfoscerate, is an unique NeuroActive form of choline that rapidly penetrates the blood brain barrier, naturally found in small amounts in milk and soybeans.

Biochemical Effects

A precursor for the neurotransmitter AcetylCholine [Supports Memory]

A precursor for PhosphatidylCholine [Supports Brain Structure]

Dose
300-2000 mg daily.

When can I feel it?
Works within a few days.

So has anyone tried any of these?

I played around with some piracetam and pramiracetam about 10 years ago. I remember feeling at the time that they were definitely having a positive effect on my mental clarity.

Piracetam works great ....

but you need some Choline source to have better effects..

when i take some Piracetam i can concentrate on difficult topics for a long time ..

Pago

Thanks for posting this! I want to get SO interested in using this stuff, it will be good for him.

I played around a bit in college, got several books - they've actually been around known as nootropics from Army research for quite a while - I met a LRP (Long Range Patrol) who had his body surgically altered to boost adrenaline output and reduce pain response, and when in the field they would consume only water and something he called zep packs which had msg to make the body feel full and lots of other liquid nutrition. Definitely a field advantage!

Look at vasopressin as well. Most of these essentially throw the throttle wide open on hormonal, neurological, and cellular mechanisms, so having the raw materials like vitamins, minerals, oils, and amino acids is crucial or you can crash and burn pretty badly - like falling asleep while driving bad.

Look carefully as side-effects and contraindications since most of the nootropics are not approved for off-label use and little research on safety and interactions is professionally studied.

Wow kinda sounds like pheromone research, eh?

D3 and B vitamins are essential, and a few amino acids thrown in as well to get the most benefit. There are formulations out there that have most of what you need in the right dosages but they will be horribly expensive - getting the bulk powders and mixing your own is expensive as well but lets you play with the dosages. There are some "compounding" pharmacies/apothecaries that will mix for you but charge a premium as well.

Wikipedia has been fairly well updated lately and is a good neutral starting point.

piracetam is awesome,I get concentration out the ying yang when i use this and its a good mood elevator without jitters it feels natural . Aniracetam is like more concentrated version of piracetam and more expensive and harder to gauge dosage and end up getting headaches even with a good choline source (i use powder form of both). Dreams are a bit weird at night more vivid too because of the choline bitartrate.if your gonna get piracetam id suggest getting a capsule making machine & capsules and buy the powder in bulk saves you money in the long run

Just picked up some piracetam and choline and have some huperzine-a lying around. Will see how it goes. Had been feeling really fatigued this fall--think it may have been a combination of seasonal affective disorder along with neurotransmitter depletion from mone usage (science people let me know if this is a valid hunch). Got a Philips goLite about a week ago and have noticed a big increase in energy and mood, and a much greater ability to concentrate. Hope to add to it with nootropics. Also back to exercising since I have energy again.

(12-19-2011 9:02 PM)CG_Jung Wrote: [ -> ]Got a Philips goLite about a week ago and have noticed a big increase in energy and mood, and a much greater ability to concentrate. Hope to add to it with nootropics. Also back to exercising since I have energy again.

You gave me a great idea about this device. I have a very erratic sleep cycle and in the winter, I hibernate, no sun at all, it's cold and dark,my mood is down... I was thinking about this kind of stuff for years but for some reason, I was seeing it as a gadget.
There seems to be some great reviews about it on Amazon and it's on sale...It's still expensive...but...Evil temptation...
Is it this one you have : http://www.amazon.com/Philips-goLITE-BLU...B001I45XL8

Do you use it in the morning ? Once a day ?

(12-19-2011 9:58 PM)NewAlpha Wrote: [ -> ]You gave me a great idea about this device. I have a very erratic sleep cycle and in the winter, I hibernate, no sun at all, it's cold and dark,my mood is down... I was thinking about this kind of stuff for years but for some reason, I was seeing it as a gadget.
There seems to be some great reviews about it on Amazon and it's on sale...It's still expensive...but...Evil temptation...
Is it this one you have : http://www.amazon.com/Philips-goLITE-BLU...B001I45XL8

Do you use it in the morning ? Once a day ?

Yes that is the device I own. Only got it about ten days ago. It is expensive, but not much more than getting AM & Glace, or some other great combo. And when you amortize the cost out over the life of the device, I think it proves more economical than taking a regimen of d3, fish oil, st. john's wort, 5HTP, antidepressants, synthetic copulins, etc.

Fact is, two weeks ago I went in to see the doctor I was that concerned about my fatigue. Got the full blood work done, and I was worried/paranoid about Lymes, hypothyroidism, SAD, serotonin depletion, etc. Still waiting for the results of the lab work, but I am already feeling much better after ten days of bluLITE usage.

I have been setting the bluLITE as an alarm in the morning and reading news on the iPad by it for 35 minutes, and maybe getting 5-10 minutes in the early-to-late afternoon as a booster. I have found my sleep better, deeper, and more consistent, my mood and energy better throughout the day, and considerably less "ADHD" feeling at work and in general (which can be a symptom of depression). My energy is the best I have felt in more than four months. And I've tried subs for motivation (they work fairly well, but not as seemingly well as this). All things considered, the last ten days there is nothing that I've added to my routine of any significance that would account for my improved mood/energy except the bluLITE.

Based on the foregoing, I would recommend it. Further down the road, I can see myself highly recommending it.

When I was in the army we had these things called go pills they gave us to test. I could work nonstop for 48hrs but would get the worst shits afterwards. I decided to give them a pass as I didn't want to have to wear diapers to use them. I'm interested in some of the things you ladies and gents are discussing. Great thread sunny10. you got reps