5alpha-androst-16-en-3alpha-ol
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5alpha-androst-16-en-3alpha-ol (3alpha-androstenol
Alpha Androstenol generally makes people more talkative and is held to have some GABAergic activity.
alpha androstenol makes women feel less agressive/more submissive while ovulating
Some have argued that a portion of alpha androstenol's effect is negated by pregnenolone, which has anti-GABAergic activity and is excitatory.
Alpha Androstenol is used, along with androstenone in the product Boar Mate which causes female pigs to assume the mating position.
We examined the effects of 5alpha-androst-16-en-3alpha-ol (3alpha-androstenol) on pulsatile luteinizing hormone (LH) secretion in human females. The frequency of the LH pulse in the follicular phase was decreased by exposing the women to 3alpha-androstenol.
(Other studies say that exposure to alpha androstenol increases luteinizing hormone? Is volume increased but pulse frequency decreased?)
The influence of androstenol – a putative human pheromone – on mood throughout the menstrual cycle. Each morning for a month female subjects placed either 5 alpha-androst-16-en-3 alpha-ol, a putative human pheromone, or a placebo on the upper lip. Each evening the subjects rated on five scales their moods during that day. In the middle of their monthly cycle those females exposed to androstenol rather than a control tended to rate their moods as submissive rather than aggressive. The compound did not significantly influence ratings of being happy/depressed; lethargic/lively; sexy/unsexy; irritable/good-tempered. The results are discussed in terms of the possible increased olfactory sensitivity of the human female to androstenol in the middle of her monthly cycle.