oils can last to the next day and Androstadienone is one sticky bastard especially in oil.i suffer from Androstadienone depression,therefore I bought cohesion oil.this formula is awesome! 1 drop is all I need and no depression at all.yesterday I applied a drop in the morning,got home in the afternoon and had a shower without scrubbing it off.this morning I thought the oil Androstadienone should be gone,so I applied another drop and went to work.oh boy I was so wrong! the drop from yesterday's morning was still kicking doing it thang,with another drop the depression hit me like a truck.what a horrible day at work.so yeah people oils REALLY last,and Androstadienone is a sticky molecule.make sure to scrub off the mones with soap and warm water