thundr
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2-Androstenol
09-17-2012 11:37 AM
Here's a nice little number I want to get my claws on. I've seen it during a few late night reading sessions and never really thought much about it. Now I have decided to put a bit more focus on it.
I came across this tidbit on my travels in the rabbit hole.
Quote:when ingested orally and passed into the bloodstream certain sex pheromones, such as 2-Androstenol, can have a profound physiological effect upon users, and their immediate behavior. 2-Androstenol is a naturally occurring sex pheromone produced in the adrenal glands and found in human sweat glands, and also in various animal sources such as elephants and goats(3,4). Sex pheromones indicate the availability of the female for reproduction; however, human males no longer seem to be able to sense these airborne chemical messages from women, yet their effects once in the bloodstream still remain quite profound. 2-Androstenol has demonstrated a strong ability to increase aggression, enhance the alpha-male attitude, and increase secretion of luteinizing hormone, which is a key hormone in the signaling of testosterone production(5,6,7). This is important because elevation in these behaviors increase the likelihood of reproduction. Ever see two male bulls compete for the right to mate with a female? There’s some pretty intense physical and aggressive behavior displayed while dominance is battled. Translate these behaviors over to human performance in the gym, and now we’re talking about some serious Alpha Male attitude to generate some serious lean mass. Attitude is everything, as attitude determines performance, and performance determines your results.
Hell, after reading some of that I am tempted to try it orally as well as pheromone testing. Dam right..
Any thoughts or comments on this molecule?
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09-17-2012 11:37 AM
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RE: 2-Androstenol
Yesterday 11:34 AM
If found in the sweat glands it must have a fairly robust pathway to excretion.
It appears to be Androst-2-ene-17b-ol which was named 2-androstenol by the manufacturer ( http://www.androcycle.com/3-ad-prohormone/)
I looked up some references :
http://prohormonedb.com/view-ingredients...none&i=205
http://supplementsciencenews.blogspot.co...enetx.html
It appears that this has been referenced as an "elephant pheromone" and was the molecular basis for a now illegal steroid implicated in the Balco scandal and Olympians failing doping tests :
http://androgenetx.blogspot.com/2011/09/...urity.html
This references the now-banned Desoxymethyltestosterone (Pheraplex, DMT, Madol) (17a-methyl-etioallocholan-2-ene-17b-ol also referenced as
17a-methyl-5a-androst-2-ene-17b-ol), and states that it is structurally similar to delta 2-Androstenol : http://www.androfactory.com/category-s/1879.htm
So are Androst-2-ene-17b-ol and delta 2-Androstenol the same thing? Very few references to Androst-2-ene-17b-ol so maybe it is a nomenclature issue?
This reference says ( http://prohormonedb.com/view-ingredients...none&i=205)
Quote:Delta 2-androstenone AKA delta-2-androst-17-one, which is more formally known as 5a-androst-2-ene-17-one
, so I'm getting confused now. Further in it says that delta-2-androst-17-one converts to 2-androstenol, so maybe this is the real deal! Yay!
Quote:With relation to steroid structure and function this compound's activity is quite simple. By the most basic definition it is a steroid. More specifically it is a pheromone. In vivo it reacts as a prohormone would, but because delta-2-androst-17-one is a preexisting metabolite of DHEA and is also found as an androsterone metabolite on the human skin it can ultimately be called a human pheromone with prohormone like activity. In this case this pheromone converts to another pheromone, 2-androstenol, which is a non-orally active version of Madol AKA Desoxymethyltestosterone. Madol was commercially released by Anabolic Xtreme as Phera-Plex. Delta-2 is closely related to Madol/Desoxymethyltestosterone except for the D ring constituents.
I think you found something interesting here, Thundr!
So if it is an elephant/human pheromone I'd expect it to do something at least! Cook some up and see what it does? I wonder if a particular salt like a sulfate or chloride would fly off better and get to the receptors best?
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Yesterday 11:34 AM
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RE: 2-Androstenol
Yesterday 12:58 PM
Ha cool! Looks murky - any clue what kind of concentration it wound up at per spray and what impurities are present?
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Yesterday 12:58 PM
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RE: 2-Androstenol
Yesterday 7:23 PM
Heh I hope it works out - elephant musth is a nasty gross thing but critical to their aggression phases when bulls fight over males - they piss all over their hind legs basically, I guess kinda similar to the way we slather ourselves in pheromones as far as effect goes. If the cat is picking up on it that is a great sign! I'd try down to a 2-3 mcg dilution and see if it has effect, it may be very powerful!
Fun Kit
Alpha Dream - L2K, Fast Burn & Slow Burn Glace, Alfa Maschio, Androstadienone, Pregnenolone
Luv Essentials - MAG, Aware
HAX - Wingman Element X, Wingman Element 9+O
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Homebrew - D3, Pregnenolone, 7-Keto DHEA
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Yesterday 7:23 PM
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