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2-Androstenol
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thundr
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Post: #1
2-Androstenol
09-17-2012 11:37 AM

Here's a nice little number I want to get my claws on. I've seen it during a few late night reading sessions and never really thought much about it. Now I have decided to put a bit more focus on it.

I came across this tidbit on my travels in the rabbit hole.

Quote:when ingested orally and passed into the bloodstream certain sex pheromones, such as 2-Androstenol, can have a profound physiological effect upon users, and their immediate behavior. 2-Androstenol is a naturally occurring sex pheromone produced in the adrenal glands and found in human sweat glands, and also in various animal sources such as elephants and goats(3,4). Sex pheromones indicate the availability of the female for reproduction; however, human males no longer seem to be able to sense these airborne chemical messages from women, yet their effects once in the bloodstream still remain quite profound. 2-Androstenol has demonstrated a strong ability to increase aggression, enhance the alpha-male attitude, and increase secretion of luteinizing hormone, which is a key hormone in the signaling of testosterone production(5,6,7). This is important because elevation in these behaviors increase the likelihood of reproduction. Ever see two male bulls compete for the right to mate with a female? There’s some pretty intense physical and aggressive behavior displayed while dominance is battled. Translate these behaviors over to human performance in the gym, and now we’re talking about some serious Alpha Male attitude to generate some serious lean mass. Attitude is everything, as attitude determines performance, and performance determines your results.

Hell, after reading some of that I am tempted to try it orally as well as pheromone testing. Dam right..

Any thoughts or comments on this molecule?

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09-17-2012 11:37 AM
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Post: #2
RE: 2-Androstenol
Yesterday 9:18 AM

This caught my attention aswell.

Would you just use it as a supplement or make pheromones from it? Which supplier? I'd be very interested in trying this one
(This post was last modified: Yesterday 9:19 AM by Thoth.)
Yesterday 9:18 AM
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Post: #3
RE: 2-Androstenol
Yesterday 11:34 AM

If found in the sweat glands it must have a fairly robust pathway to excretion.
It appears to be Androst-2-ene-17b-ol which was named 2-androstenol by the manufacturer (http://www.androcycle.com/3-ad-prohormone/)

I looked up some references :

http://prohormonedb.com/view-ingredients...none&i=205

http://supplementsciencenews.blogspot.co...enetx.html

It appears that this has been referenced as an "elephant pheromone" and was the molecular basis for a now illegal steroid implicated in the Balco scandal and Olympians failing doping tests :
http://androgenetx.blogspot.com/2011/09/...urity.html

This references the now-banned Desoxymethyltestosterone (Pheraplex, DMT, Madol) (17a-methyl-etioallocholan-2-ene-17b-ol also referenced as
17a-methyl-5a-androst-2-ene-17b-ol), and states that it is structurally similar to delta 2-Androstenol : http://www.androfactory.com/category-s/1879.htm

So are Androst-2-ene-17b-ol and delta 2-Androstenol the same thing? Very few references to Androst-2-ene-17b-ol so maybe it is a nomenclature issue?

This reference says (http://prohormonedb.com/view-ingredients...none&i=205)

Quote:Delta 2-androstenone AKA delta-2-androst-17-one, which is more formally known as 5a-androst-2-ene-17-one
, so I'm getting confused now. Further in it says that delta-2-androst-17-one converts to 2-androstenol, so maybe this is the real deal! Yay!

Quote:With relation to steroid structure and function this compound's activity is quite simple. By the most basic definition it is a steroid. More specifically it is a pheromone. In vivo it reacts as a prohormone would, but because delta-2-androst-17-one is a preexisting metabolite of DHEA and is also found as an androsterone metabolite on the human skin it can ultimately be called a human pheromone with prohormone like activity. In this case this pheromone converts to another pheromone, 2-androstenol, which is a non-orally active version of Madol AKA Desoxymethyltestosterone. Madol was commercially released by Anabolic Xtreme as Phera-Plex. Delta-2 is closely related to Madol/Desoxymethyltestosterone except for the D ring constituents.

I think you found something interesting here, Thundr!

So if it is an elephant/human pheromone I'd expect it to do something at least! Cook some up and see what it does? I wonder if a particular salt like a sulfate or chloride would fly off better and get to the receptors best?

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Alpha Dream - L2K, Fast Burn & Slow Burn Glace, Alfa Maschio, Androstadienone, Pregnenolone
Luv Essentials - MAG, Aware
HAX - Wingman Element X, Wingman Element 9+O
True Pheromones - True Alpha oil, True Instinct oil, True Love, The Gilroy patches
Homebrew - D3, Pregnenolone, 7-Keto DHEA
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thundr
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Post: #4
RE: 2-Androstenol
Yesterday 12:01 PM

(Yesterday 11:34 AM)2Soon2Care Wrote:  Cook some up and see what it does? I wonder if a particular salt like a sulfate or chloride would fly off better and get to the receptors best?


[Image: scaled.php?server=843&filename=d...es=landing]


Already on the burner my friend. LOL Just havent had the time to mess with it yet.

Delta-2-androst-17-one is the stuff I bought recently from androgenetx.

And while it has been cooking I have been taking it orally as well. No real notable effects yet so I guess it needs a buildup in the system.

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Post: #5
RE: 2-Androstenol
Yesterday 12:58 PM

Ha cool! Looks murky - any clue what kind of concentration it wound up at per spray and what impurities are present?

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Luv Essentials - MAG, Aware
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thundr
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Post: #6
RE: 2-Androstenol
Yesterday 1:34 PM

LOL Yeah its very murky. Plus I shook it up again before I snapped the pic. The color is the naringin flavonoids that I assume were in the product to enhance absorption. I dont see them making much difference as they are pretty much just pigmentation at this point.

100mg of delta 2 is dissolving in 9 ml of etoh. This is the new batch I just made bc the other one got knocked over by one of the animals and leaked. I had to hide this last batch in the cabinet bc the cat is all up on this product for some reason. Maybe it can smell the animal origin, idk. Hopefully females will replicate this reaction to it. LOL

This week when it settles I will extract it and add additional 21 ml making it 3.34 mg per ml. This will make it about 250 mcg per drop. Gonna put one drop in 1.5 ml, fix it at 10% and make 10.4 mcg per spray and see how that runs.

EDIT: had to correct from dissolving in 8 ml to 9 ml as I saw this when I put the label back on the bottle after its photoshoot.

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Post: #7
RE: 2-Androstenol
Yesterday 1:51 PM

(Yesterday 1:34 PM)thundr Wrote:  This is the new batch I just made bc the other one got knocked over by one of the animals and leaked. I had to hide this last batch in the cabinet bc the cat is all up on this product for some reason. Maybe it can smell the animal origin, idk. Hopefully females will replicate this reaction to it. LOL



now we´re onto something ..

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Post: #8
RE: 2-Androstenol
Yesterday 7:23 PM

Heh I hope it works out - elephant musth is a nasty gross thing but critical to their aggression phases when bulls fight over males - they piss all over their hind legs basically, I guess kinda similar to the way we slather ourselves in pheromones as far as effect goes. If the cat is picking up on it that is a great sign! I'd try down to a 2-3 mcg dilution and see if it has effect, it may be very powerful!

Fun Kit
Alpha Dream - L2K, Fast Burn & Slow Burn Glace, Alfa Maschio, Androstadienone, Pregnenolone
Luv Essentials - MAG, Aware
HAX - Wingman Element X, Wingman Element 9+O
True Pheromones - True Alpha oil, True Instinct oil, True Love, The Gilroy patches
Homebrew - D3, Pregnenolone, 7-Keto DHEA
Yesterday 7:23 PM
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thundr
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Post: #9
RE: 2-Androstenol
Today 10:57 AM

[Image: scaled.php?server=405&filename=p...es=landing]

If you look close you can see the delta none crystals in the micronized flavonoids. At some point this week I am going to break open a few more caps and remove the larger none crystals with a pair of tweezers.

I have no way of measuring such a small amount of product that may net a few mere mgs. My scale does not go that far down so Im going to have to wing it and estimate. I will be sacrificing precision for purity in this next batch.

LOL the things I do for science.. hehe tweezers.

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Post: #10
RE: 2-Androstenol
Today 1:09 PM

As a woman, I would love to try this one around the BF.
Today 1:09 PM
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